Top 20 Mainstream Songs of May
| 1 | Boyfriend | Justin Bieber | |
| 2 | Eyes Open | Taylor Swift | |
| 3 | Dance Again | Jennifer Lopez f./Pitbull | |
| 4 | The Fighter | Gym Class Heroes f./Ryan Tedder | |
| 5 | Hit The Lights | Promo Only Clean Edit | Selena Gomez & The Scene |
| 6 | Back In Time | Pitbull f./Chris Brown | |
| 7 | Girl Gone Wild | Madonna | |
| 8 | Everybody Talks | Neon Trees | |
| 9 | Too Close | Alex Clare | |
| 10 | Primadonna | Marina & The Diamonds | |
| 11 | For You | Viennie V | |
| 12 | Tongue Tied | Grouplove | |
| 13 | Want U Back | Cher Lloyd | |
| 14 | Blink | U.V.U.K. | |
| 15 | Changed The Way You Kiss Me | Example f./Ludacris | |
| 16 | Don’t Give Up | Main Clean Edit | Kevin Rudolf |
| 17 | Don’t Give Up | Rhythmic Remix | Kevin Rudolf |
| 18 | La La | The Cab | |
| 19 | Turn All The Lights On | Promo Only Clean Edit | T-Pain f./Ne-Yo |
| 20 | Another Rainbow |
